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Tesofensine
Clinical
Research chemical
Summary
Oral triple monoamine reuptake inhibitor (dopamine, norepinephrine, serotonin) studied for substantial weight loss; not a peptide but listed in oral research-capsule catalogs.
Categories
Metabolic & Body Comp, Cognitive & Nootropic
Mechanism
Inhibits reuptake of DA/NE/5-HT, reducing appetite and increasing energy expenditure indirectly via central monoamine tone.
Half-life
~220 hours (very long; active metabolites)
Routes
Oral
Legal / access
Not currently an approved obesity drug in the US. Research chemical / capsule listings only.
Key risks
- Heart rate and blood pressure increases
- Insomnia
- Dry mouth
- Mood changes
Common claims
- Powerful oral appetite suppression
- Stimulant-leaning fat loss
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