Reconstitution
5 mg vial
CGL5

Cagrilintide 5 mg

Educational recon guide for a 5 mg Cagrilintide research vial and weekly unit mapping. Research use only — investigational amylin analogue.

Vial size

Same research phases — calculator defaults and unit math match the selected vial strength.

Vial

5 mg

Your BAC water

1 mL

Concentration

5.00 mg/mL

Per unit

~50.0 mcg

Frequency

Once weekly (same weekday)

Route

Subcutaneous

Live reconstitution calculator

Defaults match this guide (5 mg + 1 mL BAC). Change water or dose and the unit tables below update automatically.

Step 1

Reconstitution

Peptide amount in the vial and how much bacteriostatic water you add.

Bacteriostatic water (mL)
Concentration5 mg/mL
Per 1 unit (0.01 mL)50 mcg
Per 10 units (0.1 mL)500 mcg

Step 2

Your dose

This guide uses microgram-scale research doses — quick picks are in mcg (100 mcg = 0.1 mg).

Desired dose

Quick select (mcg) — switch units or type any value

Insulin syringe (U-100)

Suggested: 30-unit barrel (smallest that fits this draw).

Your draw

Results

Total draw

5 units

Volume

0.050 mL

Doses per vial

20

Syringes needed

1

Barrel

30-unit

Fits one syringe?

Yes

30-unit · 0.3 mL

Filled to 5 u

Fill one 30-unit U-100 syringe to about 5 units (0.050 mL).

Weekly research phases

Units and volumes recompute from your Step 1 concentration (1 mL BAC → 5.00 mg/mL · 50.0 mcg/unit).

Standard titration

Published research titrations commonly start around ~0.25–0.3 mg once weekly and step upward (examples include ladders toward ~2.4 mg weekly, with higher monotherapy arms studied up to ~4.5 mg weekly). GI tolerability drives slow titration.

Live from Step 1
PhaseWeekly doseUnitsVolume
Weeks 1–4250 mcg0.25 mg5 u0.05 mLCommon educational start (~0.25 mg weekly)
Weeks 5–8500 mcg0.5 mg10 u0.10 mL
Weeks 9–121 mg1,000 mcg20 u0.20 mL
Weeks 13–161.70 mg1,700 mcg34 u0.34 mL
Weeks 17+2.40 mg2,400 mcg48 u0.48 mLCommon maintenance discussion range in dual-pathway obesity research

Advanced / higher-end

Faster escalation discussed in research communities — not a clinical recommendation

Live from Step 1
PhaseWeekly doseUnitsVolume
Higher monotherapy arm · 4.5 mg weekly4.50 mg4,500 mcg90 u0.90 mLUpper end of some monotherapy dose-finding work — check syringe capacity vs recon water

Supplies planner

Using the guide’s phase ladder (250 mcg → 500 mcg → 1 mg weekly (phase ladder)) over a 12-week schedule. Set a dose in Step 2 to plan supplies at your own amount.

Updates with calculator

Your recon

1 mL · 5.00 mg/mL

Dose in plan

Phase ladder

Syringe size

100-unit

Horizon

12-week schedule

Cagrilintide 5 mg vials

2 vials

~7 mg mg total peptide over this 12-week schedule at 250 mcg → 500 mcg → 1 mg weekly (phase ladder). Each vial holds 5 mg.

Bacteriostatic water

1 × 3 mL bottle

1 mL BAC per vial × 2 vials = 2.0 mL total. Buy as 1× 3 mL bottle or 1× 10 mL bottle (whichever you stock).

U-100 insulin syringes (100-unit)

12+ syringes

About one 100-unit syringe per injection for this schedule. Keep a few spares.

Alcohol swabs & sharps

~28 swabs · 1 sharps container

Wipe vial stopper and injection site each time. Dispose needles in a proper sharps container.

Reconstitution steps

  1. Allow the lyophilized 5 mg Cagrilintide vial and bacteriostatic water to reach room temperature.
  2. Draw 1.0 mL bacteriostatic water (default for this guide).
  3. Inject BAC slowly down the inner wall of the vial — avoid blasting the powder cake.
  4. Gently swirl or roll until the solution is clear. Do not shake hard (foaming).
  5. Label with recon date and concentration (e.g. "5.0 mg/mL — 1 mL BAC").
  6. Refrigerate at 2–8 °C (35–46 °F), protected from light. Prefer using a reconstituted multi-dose vial within ~28 days with sterile technique.

Storage

Lyophilized

Keep dry powder cold and dark when possible (−20 °C / −4 °F preferred for long-term research stock).

Reconstituted

Refrigerate at 2–8 °C (35–46 °F). Avoid freeze–thaw of the working solution. Prefer finishing within ~28 days.

  • ·Write recon date and BAC volume on the label.
  • ·Protect from light during storage.
  • ·Discard if cloudy, particulates, or odd odor appear after reconstitution.

Protocol notes

  • ·Cagrilintide is a long-acting amylin analogue studied for obesity (alone and with GLP-1 agonists).
  • ·Research powders are not the same as clinical trial drug product.
  • ·Often discussed with semaglutide (CagriSema) — see the Cagri+Sema blend guides for fixed dual vials.
  • ·Research use only.

Research context & considerations

Cagrilintide activates amylin pathways involved in satiety and gastric emptying. Clinical development includes monotherapy and combination programs with semaglutide. Catalog research vials are educational recon materials only.

  • ·GI effects (nausea, etc.) are commonly discussed for amylin/GLP-1 pathway agents.
  • ·Not FDA-approved as a research-vial consumer product.
  • ·Pregnancy and pediatric use out of scope.

Catalog match

Cagrilintide (CGL5)

5mg x 10 vials · from $45

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