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Matrixyl (Palmitoyl Pentapeptide-4)
Limited
Research chemical
Summary
Palmitoylated pentapeptide widely used in cosmetic anti-aging formulations to stimulate collagen and extracellular-matrix remodeling signals.
Categories
Skin & Aesthetic
Mechanism
Fragment related to type I collagen propeptide signaling; stimulates fibroblasts to increase collagen I/III, fibronectin, and matrix proteins in vitro and in cosmetic clinical photography studies.
Half-life
Topical local kinetics
Routes
Topical
Legal / access
Established cosmetic ingredient; research vials are not drug products.
Key risks
- Mild irritation
- Sensitization rare
Common claims
- Firmer skin
- Reduced fine lines
- Pair with GHK-Cu and retinoids
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