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MGF (Mechano Growth Factor)
Preclinical
Research chemical
Summary
Splice variant of IGF-1 expressed in response to mechanical overload; researched for localized muscle repair. Short half-life; PEGylated MGF is the stabilized catalog cousin.
Categories
Growth Hormone Axis, Performance
Mechanism
Localized IGF-1 receptor and distinct C-terminal domain signaling associated with muscle repair and hyperplasia-related pathways in preclinical literature.
Half-life
Very short (minutes) for native MGF
Routes
Subcutaneous injection; Intramuscular injection
Legal / access
Research growth factor. Not approved for muscle building.
Key risks
- Hypoglycemia risk (IGF axis)
- Injection trauma
- Unknown long-term safety
Common claims
- Localized muscle growth
- Injury repair inject near muscle
- Training adaptation
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