MGF (Mechano Growth Factor)
Also known as MGF · IGF-1 Ec · mechano growth factor
New
Reconstitution & dosing guide
2 mg vial — research phases, recon steps, and a live unit calculator.
Available sizes & price
Catalog only2mg x 10 vials
MGF · Not in current stock
$25 / vial
Prices per vial · Research use only · Not medical advice.
Splice variant of IGF-1 expressed in response to mechanical overload; researched for localized muscle repair. Short half-life; PEGylated MGF is the stabilized catalog cousin.
How to picture it
After hard mechanical stress, muscle tissue issues a local repair broadcast linked to IGF-Ec signaling and satellite-cell activity. Native MGF is short-lived — a neighborhood text, not a system-wide announcement. Picture localized muscle-repair signaling right where loading happened, before PEGylation extends the message.
Research focus & benefits
- Local muscle repair and IGF-Ec research
- Satellite-cell and mechanical-load studies
- Short-acting MGF pathway interest
Benefits describe research interest and pathway rationale — not guaranteed outcomes or medical advice. Research use only.
Overview
Mechano Growth Factor is the IGF-1Ec splice variant upregulated in muscle after stretch/damage. It is studied for autocrine repair and satellite-cell activation. Native MGF is rapidly degraded; PEG-MGF extends activity. Catalog often lists both 2 mg vials.
Mechanism
Localized IGF-1 receptor and distinct C-terminal domain signaling associated with muscle repair and hyperplasia-related pathways in preclinical literature.
Research uses
- Muscle damage and overload models
- Satellite cell activation research
- Comparison with IGF-1 LR3 and PEG-MGF
Research dosing notes
Research discussions often use local mcg injections post-training. PEG-MGF used when longer action desired. No clinical standard.
Half-life / kinetics
Very short (minutes) for native MGF
Common research routes
Reported considerations
- Hypoglycemia risk (IGF axis)
- Injection trauma
- Unknown long-term safety
Contraindications / cautions
- Active cancer
- Diabetic hypoglycemia risk
- Pregnancy
Common research stacks
- PEG-MGF
- IGF-1 LR3
- CJC/Ipamorelin
Legal / access note
Research growth factor. Not approved for muscle building.