Compare peptides
Put two entries side by side — evidence, mechanism, risks, and community claims.
Sermorelin
Clinical
Compounded / restricted
Summary
GHRH (1-29) analog historically used diagnostically and therapeutically to stimulate endogenous GH.
Categories
Growth Hormone Axis, Longevity
Mechanism
Stimulates pituitary GH release via GHRH receptors, preserving feedback loops more closely than exogenous rHGH.
Half-life
Short (minutes to under an hour)
Routes
Subcutaneous injection
Legal / access
Has a clinical history of approval for specific uses; current compounding and availability vary. Not a free research free-for-all in regulated clinics.
Key risks
- Flushing
- Injection-site pain
- Headache
- Hyperactivity or sleep changes
Common claims
- More natural GH pulses than injecting HGH
- Improved sleep architecture
- Age-management support under medical supervision
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