Skin & Aesthetic
Clinical
FDA-approved (specific use)

Melanotan I

Also known as Afamelanotide · Scenesse · NDP-MSH

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Reconstitution & dosing guide

10 mg vial — research phases, recon steps, and a live unit calculator.

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Available sizes & price

Catalog only

10mg x 10 vials

MelanotanI · Not in current stock

$20 / vial

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Prices per vial · Research use only · Not medical advice.

Melanocortin analog; afamelanotide is approved for erythropoietic protoporphyria photoprotection — distinct from MT-II tan use.

How to picture it

More focused on pigmentation and photoprotection-related melanocortin signaling than MT-II's broader spillover. Picture a cleaner key on the same melanocortin keychain — a more dedicated "produce melanin / pigment system" story within the receptor family, closer to afamelanotide-related photoprotection biology than to multi-system arousal spillover.

Research focus & benefits

  • Pigmentation and photoprotection research
  • Selective melanocortin pathway interest
  • Cleaner tanning-system framing vs MT-II

Benefits describe research interest and pathway rationale — not guaranteed outcomes or medical advice. Research use only.

Overview

Melanotan I (afamelanotide) is a linear analog of alpha-MSH. As Scenesse, it is an approved implant for preventing phototoxicity in erythropoietic protoporphyria. This is pharmacologically related to but clinically different from Melanotan II tanning misuse.

Mechanism

MC1R agonism increasing eumelanin without the same nonselective profile as MT-II.

Research uses

  • EPP photoprotection (approved)
  • Photosensitivity disorders research
  • Pigmentation biology

Research dosing notes

Approved product is a controlled implant by specialists — not a research vial tanning protocol.

Open full reconstitution & dosing guide →

Half-life / kinetics

Implant formulation provides prolonged exposure

Common research routes

Subcutaneous injection

Reported considerations

  • Nausea
  • Flushing
  • Implant-site reactions
  • Pigment changes

Contraindications / cautions

  • Per label for Scenesse
  • Pregnancy cautions
  • Melanoma surveillance needs

Common research stacks

  • Strict sun-safety still required for EPP patients

Legal / access note

Afamelanotide (Scenesse) is approved for EPP. Research Melanotan I sold for tanning is not the same as legitimate specialty care.