TB-500
Also known as Thymosin Beta-4 fragment · Tβ4 · Thymosin β4
New
Reconstitution & dosing guide
2 mg · 5 mg · 10 mg vial sizes — research phases, recon steps, and a live unit calculator.
Available sizes & price
Catalog only10mg x 10 vials
TB500 (BT10) · Not in current stock
$40 / vial
2mg x 10 vials
TB500 (BT2) · Not in current stock
$20 / vial
5mg x 10 vials
TB500 (BT5) · Not in current stock
$25 / vial
Prices per vial · Research use only · Not medical advice.
Synthetic peptide related to thymosin beta-4, used in recovery communities for systemic tissue repair and flexibility.
How to picture it
Cells can't repair what they can't reach. TB-500 (a thymosin β4 fragment) is studied for actin dynamics — the cytoskeleton's ability to reorganize so cells can move — and for shifting immune cells toward less destructive inflammation. Picture a traffic director for recovery logistics: not shouting louder at the injury, but helping the right repair cells travel into the damaged zone and reorganize scaffolding. That migration-and-structure role is why it pairs so often with local repair signals like BPC-157.
Research focus & benefits
- Cell migration and actin-related recovery research
- Soft-tissue repair and systemic recovery interest
- Anti-inflammatory macrophage polarization signals in models
- Popular pairing with BPC-157 in dual-repair stacks
Benefits describe research interest and pathway rationale — not guaranteed outcomes or medical advice. Research use only.
Overview
TB-500 is a synthetic version of a portion of thymosin beta-4, a naturally occurring peptide involved in actin regulation and cell migration. Unlike more localized recovery peptides, it is often discussed as having more systemic distribution. It is frequently paired with BPC-157 in the so-called Wolverine stack.
Mechanism
Thymosin beta-4 sequesters G-actin and influences cell motility, angiogenesis, and inflammation resolution in preclinical models. TB-500 is marketed as a more stable synthetic analog used to pursue similar recovery pathways.
Research uses
- Cardiac and dermal wound-healing models
- Corneal and soft-tissue repair research
- Inflammation and fibrosis studies
Research dosing notes
Research-community protocols often use loading phases followed by lower maintenance frequency. Exact milligram ranges vary widely; no approved clinical dosing for sports recovery exists.
Half-life / kinetics
Longer than many short peptides; community protocols often use less frequent dosing
Common research routes
Reported considerations
- Lethargy or head pressure (anecdotal)
- Injection-site reactions
- Unknown long-term risks
Contraindications / cautions
- Cancer history (theoretical)
- Pregnancy
- Competitive athletes under drug testing
Common research stacks
- BPC-157
- GH secretagogues
- GHK-Cu
Legal / access note
Not approved as a drug for recovery or sports use. Restricted in sport and often sold for research only.