Growth Hormone Axis
Performance
Longevity
Limited
Research chemical

CJC-1295

Also known as CJC-1295 without DAC · Mod GRF 1-29 · CJC-1295 with DAC

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Reconstitution & dosing guide

2 mg · 5 mg · 10 mg vial sizes — research phases, recon steps, and a live unit calculator.

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Available sizes & price

Catalog only

10mg x 10 vials

CJC 1295 (without DAC) (CND10) · Not in current stock

$35 / vial

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2mg x 10 vials

CJC 1295 (without DAC) (CND2) · Not in current stock

$15 / vial

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5mg x 10 vials

CJC 1295 (without DAC) (CND5) · Not in current stock

$20 / vial

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Prices per vial · Research use only · Not medical advice.

GHRH analog that stimulates natural growth-hormone pulses; used with GHRPs for body composition and recovery goals.

How to picture it

Your hypothalamus normally sends GHRH pulses that tell the pituitary "release growth hormone now." CJC-1295 is a stabilized GHRH-family message that knocks on that same pituitary door. With DAC it wears a long "stay in circulation" backpack so the signal lingers for days; without DAC it behaves more like a timed doorbell — pulse, then quiet. The educational picture is axis engagement: ask the pituitary to release GH, rather than injecting finished growth hormone, with a design choice between physiologic rhythm and sustained elevation.

Research focus & benefits

  • Endogenous GH pulse or sustained GH/IGF-1 elevation research
  • Pairs with GHRPs for larger pulse amplitude studies
  • Sleep, recovery, and body-composition pathway interest
  • More physiologic framing than exogenous rHGH replacement

Benefits describe research interest and pathway rationale — not guaranteed outcomes or medical advice. Research use only.

Overview

CJC-1295 is a modified growth hormone–releasing hormone (GHRH) analog. Two forms circulate in research markets: without DAC (often called Mod GRF 1-29; short-acting, pulse-like) and with DAC (Drug Affinity Complex; longer-acting). Biohackers typically prefer the no-DAC form with Ipamorelin to mimic physiologic GH pulses rather than flat elevation.

Mechanism

Binds GHRH receptors on pituitary somatotrophs, increasing GH secretion. With DAC, albumin binding extends half-life; without DAC, effects are short and better timed with sleep or training.

Research uses

  • GH deficiency research models
  • Body composition studies
  • Aging and recovery research contexts

Research dosing notes

Common community practice: no-DAC CJC-1295 + Ipamorelin before bed, sometimes post-workout. DAC forms are less popular due to non-physiologic GH elevation and side-effect reports.

Open full reconstitution & dosing guide →

Half-life / kinetics

No DAC: ~30 minutes; With DAC: multi-day

Common research routes

Subcutaneous injection

Reported considerations

  • Water retention
  • Tingling / numbness
  • Increased hunger (more with some GHRPs)
  • Possible IGF-1 elevation concerns long-term

Contraindications / cautions

  • Active cancer
  • Uncontrolled diabetes
  • Pregnancy
  • Proliferative retinopathy risk

Common research stacks

  • Ipamorelin
  • GHRP-2
  • Tesamorelin
  • BPC-157

Legal / access note

Not FDA-approved. Related GHRH analogs have clinical history, but CJC-1295 research products are typically unapproved.