GDF-8 (Myostatin)
Also known as GDF-8 · Myostatin · growth differentiation factor 8
New
Reconstitution & dosing guide
1 mg vial — research phases, recon steps, and a live unit calculator.
Available sizes & price
Catalog only1mg x 10 vials
GDF-8 · Not in current stock
$70 / vial
Prices per vial · Research use only · Not medical advice.
Endogenous negative regulator of skeletal muscle growth; catalog material is typically for assay/research reference rather than use as a drug.
How to picture it
Myostatin (GDF-8) is the brake itself on muscle growth. Studying it is how science maps the limits on muscle size and how those limits might be modulated. Picture the natural governor that follistatin and ACE-031-class agents try to counter — essential research tool for understanding the pathway, not a growth promoter.
Research focus & benefits
- Myostatin pathway reference biology
- Muscle-growth limit science
- Foundation for anti-myostatin agent research
Benefits describe research interest and pathway rationale — not guaranteed outcomes or medical advice. Research use only.
Overview
Myostatin (GDF-8) is a TGF-β superfamily member that limits muscle hypertrophy. Loss-of-function mutations produce double-muscling phenotypes. Peptide catalogs listing GDF-8 are supplying the ligand for research — biohackers more often seek inhibitors (follistatin, ACE-031, antibodies) than the myostatin protein itself.
Mechanism
Binds ActRIIB (and related receptors) to activate SMAD2/3 signaling that suppresses muscle protein synthesis and satellite-cell activity.
Research uses
- Muscle biology and cachexia models
- Inhibitor screening assays
- Comparative growth-factor research
Research dosing notes
Not a performance-enhancing injectand — it is the brake on muscle growth. Research handling only.
Half-life / kinetics
Circulating latent complex; active form regulated by proteolysis
Common research routes
Reported considerations
- Would theoretically reduce muscle if bioactive and delivered systemically
Contraindications / cautions
- Not for human administration as a stack compound
Common research stacks
- Studied opposite Follistatin / ACE-031
Legal / access note
Research reagent. Not a therapeutic product for injection.